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Nanoscale Staining Sandbox

Vesicle Surface Explorer

Explore a fast browser-side preview for nanoscale vesicles, or switch into Monte Carlo mode when you want discrete packing for the current scenario.

Single-EV tetraspanin counts Membrane crowding by coverage Membrane-dye quenching benchmarks

Browser Model

Preview Or Monte Carlo Mode

Preview (fast) Monte Carlo simulation

Switching to Monte Carlo mode keeps the discrete packing model active for the current settings and reruns it as inputs change.

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Preview

Preview mode is active. Live updates stay on the fast estimate until you switch to Monte Carlo simulation.

Software Guide

How does this work?

Open a compact flowchart that explains how inputs move through the preview model, optional Monte Carlo refinement, plots, and interpretation layers.

Vesicle View

Balanced
ligand sample bound probe

Crowding

Low

Fluorophore Proximity

Low

Accessible EV surface 0 nm^2
Ligand close-pack limit 0
Curvature-aware bound-complex limit 0
Predicted bound probes 0
Equivalent ligand spacing 0 nm
Nearest fluorophore neighbor 0 nm

Parameter Sweep

Hold others fixed

Surface Packing

binding retention complex coverage

Fluorophore Proximity

close-neighbor fraction

Experimental Anchors

Data-guided

These tiles compare the current scenario against published EV and membrane-labeling regimes. They are calibration cues, not hard cutoffs.

Protein Crowding Loading…

Plasma-EV Context Loading…

Dye / Quenching Check Loading…

Model Notes